Publications

Tarca, A. L., B. P. A. Grandjean, and F. Larachi. “Integrated Genetic Algorithm - Artificial Neural Network Strategy for Modeling Important Multiphase-Flow Characteristics” 41, no. 10 (2002): 2543–51.

Tarca, Adi, Grandjean Bernard, and Faical Larachi. “Reinforcing the Phenomenological Consistency in Artificial Neural Network Modeling of Multiphase Reactors” 42, no. 8–9 (2003): 653–62.

Tarca, Adi, Bernard Grandjean, and Faical Larachi. “Artificial Neural Network Meta Models to Enhance the Prediction and Consistency of Multiphase Reactor Correlations” 42, no. 8 (2003): 1707–12.

Tarca, Adi, Grandjean Bernard, and Faical Larachi. “Designing Supervised Classifiers for Multiphase Flow Data Classification” 59, no. 16 (2004): 3303–13.

Tarca, Adi, Grandjean Bernard, and Larachi Faical. “Embedding Monotonicity and Concavity in the Training of Neural Networks by Means of Genetic Algorithms: Application to Multiphase Flow” 28, no. 9 (2004): 1701–13.

Tarca, Adi, Grandjean Bernard, and Larachi Faical. “Feature Selection for Multiphase Reactors Data Classification” 44, no. 4 (2005): 1073–84.

Tarca, A. L., J. E. K. Cooke, and J. Mackay. “A Robust Neural Networks Approach for Spatial and Intensity-Dependent Normalization of CDNA Microarray Data.” Bioinformatics (Oxford, England) 21, no. 11 (June 1, 2005): 2674–83. https://doi.org/10.1093/bioinformatics/bti397.

Romero, Roberto, Adi L. Tarca, and Gerard Tromp. “Insights into the Physiology of Childbirth Using Transcriptomics.” PLoS Medicine 3, no. 6 (June 2006): e276. https://doi.org/10.1371/journal.pmed.0030276.

Khatri, Purvesh, Valmik Desai, Adi L. Tarca, Sivakumar Sellamuthu, Derek E. Wildman, Roberto Romero, and Sorin Draghici. “New Onto-Tools: Promoter-Express, NsSNPCounter and Onto-Translate.” Nucleic Acids Research 34, no. Web Server issue (July 1, 2006): W626-631. https://doi.org/10.1093/nar/gkl213.

Tarca, Adi L., Roberto Romero, and Sorin Draghici. “Analysis of Microarray Experiments of Gene Expression Profiling.” American Journal of Obstetrics and Gynecology 195, no. 2 (August 2006): 373–88. https://doi.org/10.1016/j.ajog.2006.07.001.

Pineles, Beth L., Roberto Romero, Daniel Montenegro, Adi L. Tarca, Yu Mi Han, Yeon Mee Kim, Sorin Draghici, et al. “Distinct Subsets of MicroRNAs Are Expressed Differentially in the Human Placentas of Patients with Preeclampsia.” American Journal of Obstetrics and Gynecology 196, no. 3 (March 2007): 261.e1-6. https://doi.org/10.1016/j.ajog.2007.01.008.

Tarca, Adi L., Vincent J. Carey, Xue-wen Chen, Roberto Romero, and Sorin Draghici. “Machine Learning and Its Applications to Biology.” PLoS Computational Biology 3, no. 6 (June 2007): e116. https://doi.org/10.1371/journal.pcbi.0030116.

Khatri, Purvesh, Calin Voichita, Khalid Kattan, Nadeem Ansari, Avani Khatri, Constantin Georgescu, Adi L. Tarca, and Sorin Draghici. “Onto-Tools: New Additions and Improvements in 2006.” Nucleic Acids Research 35, no. Web Server issue (July 2007): W206-211. https://doi.org/10.1093/nar/gkm327.

Montenegro, Daniel, Roberto Romero, Beth L. Pineles, Adi L. Tarca, Yeon Mee Kim, Sorin Draghici, Juan Pedro Kusanovic, et al. “Differential Expression of MicroRNAs with Progression of Gestation and Inflammation in the Human Chorioamniotic Membranes.” American Journal of Obstetrics and Gynecology 197, no. 3 (September 2007): 289.e1-6. https://doi.org/10.1016/j.ajog.2007.06.027.

Hassan, Sonia S., Roberto Romero, Adi L. Tarca, Sorin Draghici, Beth Pineles, Andrej Bugrim, Nahla Khalek, et al. “Signature Pathways Identified from Gene Expression Profiles in the Human Uterine Cervix before and after Spontaneous Term Parturition.” American Journal of Obstetrics and Gynecology 197, no. 3 (September 2007): 250.e1-7. https://doi.org/10.1016/j.ajog.2007.07.008.

Draghici, Sorin, Purvesh Khatri, Adi Laurentiu Tarca, Kashyap Amin, Arina Done, Calin Voichita, Constantin Georgescu, and Roberto Romero. “A Systems Biology Approach for Pathway Level Analysis.” Genome Research 17, no. 10 (October 2007): 1537–45. https://doi.org/10.1101/gr.6202607.

Lin, Ho-Sheng, Harvinder S. Talwar, Adi L. Tarca, Alexei Ionan, Madhumita Chatterjee, Bin Ye, Jerzy Wojciechowski, et al. “Autoantibody Approach for Serum-Based Detection of Head and Neck Cancer.” Cancer Epidemiology, Biomarkers & Prevention : A Publication of the American Association for Cancer Research, Cosponsored by the American Society of Preventive Oncology 16, no. 11 (November 2007): 2396–2405. https://doi.org/10.1158/1055-9965.EPI-07-0318.

Santolaya-Forgas, Joaquin, Samuel Edwin, Katie Zeiter, Adam Pitt, Beth Pineles, Adi L. Tarca, Jimmy Espinoza, et al. “The Timed-Pregnant Baboon Animal Model Can Be Used for Determining the Role of Soluble Vascular Endothelial Growth Factor Receptors 1 and 2 during Development.” Journal of Medical Primatology 36, no. 6 (December 2007): 370–74. https://doi.org/10.1111/j.1600-0684.2006.00205.x.

Draghici, Sorin, Adi L. Tarca, Longfei Yu, Stephen Ethier, and Roberto Romero. “KUTE-BASE: Storing, Downloading and Exporting MIAME-Compliant Microarray Experiments in Minutes Rather than Hours.” Bioinformatics (Oxford, England) 24, no. 5 (March 1, 2008): 738–40. https://doi.org/10.1093/bioinformatics/btm559.

Toft, Johanne Holm, Ingrid Alsos Lian, Adi Laurentiu Tarca, Offer Erez, Jimmy Espinoza, Irina Poliakova Eide, Line Bjorge, Sorin Draghici, Roberto Romero, and Rigmor Austgulen. “Whole-Genome Microarray and Targeted Analysis of Angiogenesis-Regulating Gene Expression (ENG, FLT1, VEGF, PlGF) in Placentas from Pre-Eclamptic and Small-for-Gestational-Age Pregnancies.” The Journal of Maternal-Fetal & Neonatal Medicine : The Official Journal of the European Association of Perinatal Medicine, the Federation of Asia and Oceania Perinatal Societies, the International Society of Perinatal Obstetricians 21, no. 4 (April 2008): 267–73. https://doi.org/10.1080/14767050801924118.

Separovic, Duska, Louie Semaan, Adi L. Tarca, Ma’In Yehya Awad Maitah, Kentaro Hanada, Jacek Bielawski, Maristella Villani, and Chiara Luberto. “Suppression of Sphingomyelin Synthase 1 by Small Interference RNA Is Associated with Enhanced Ceramide Production and Apoptosis after Photodamage.” Experimental Cell Research 314, no. 8 (May 1, 2008): 1860–68. https://doi.org/10.1016/j.yexcr.2008.02.008.

Than, Nandor Gabor, Offer Erez, Derek E. Wildman, Adi L. Tarca, Samuel S. Edwin, Asad Abbas, John Hotra, et al. “Severe Preeclampsia Is Characterized by Increased Placental Expression of Galectin-1.” The Journal of Maternal-Fetal & Neonatal Medicine : The Official Journal of the European Association of Perinatal Medicine, the Federation of Asia and Oceania Perinatal Societies, the International Society of Perinatal Obstetricians 21, no. 7 (July 2008): 429–42. https://doi.org/10.1080/14767050802041961.

Kim, Jung-Sun, Roberto Romero, Adi Laurentiu Tarca, Christopher LaJeunesse, Yu Mi Han, Mi Jeong Kim, Yeon Lim Suh, et al. “Gene Expression Profiling Demonstrates a Novel Role for Foetal Fibrocytes and the Umbilical Vessels in Human Fetoplacental Development.” Journal of Cellular and Molecular Medicine 12, no. 4 (August 2008): 1317–30. https://doi.org/10.1111/j.1582-4934.2008.00284.x.

Than, Nandor Gabor, Omar Abdul Rahman, Rita Magenheim, Balint Nagy, Tibor Fule, Beata Hargitai, Marei Sammar, et al. “Placental Protein 13 (Galectin-13) Has Decreased Placental Expression but Increased Shedding and Maternal Serum Concentrations in Patients Presenting with Preterm Pre-Eclampsia and HELLP Syndrome.” Virchows Archiv : An International Journal of Pathology 453, no. 4 (October 2008): 387–400. https://doi.org/10.1007/s00428-008-0658-x.

Than, Nandor Gabor, Sung-Su Kim, Asad Abbas, Yu Mi Han, John Hotra, Adi L. Tarca, Offer Erez, et al. “Chorioamnionitis and Increased Galectin-1 Expression in PPROM --an Anti- Inflammatory Response in the Fetal Membranes?” American Journal of Reproductive Immunology (New York, N.Y. : 1989) 60, no. 4 (October 2008): 298–311. https://doi.org/10.1111/j.1600-0897.2008.00624.x.

Than, Nandor Gabor, Roberto Romero, Offer Erez, Juan Pedro Kusanovic, Adi L. Tarca, Samuel S. Edwin, Jung-Sun Kim, et al. “A Role for Mannose-Binding Lectin, a Component of the Innate Immune System in Pre-Eclampsia.” American Journal of Reproductive Immunology (New York, N.Y. : 1989) 60, no. 4 (October 2008): 333–45. https://doi.org/10.1111/j.1600-0897.2008.00631.x.

Than, Nandor Gabor, Roberto Romero, Offer Erez, Amy Weckle, Adi L. Tarca, John Hotra, Asad Abbas, et al. “Emergence of Hormonal and Redox Regulation of Galectin-1 in Placental Mammals: Implication in Maternal-Fetal Immune Tolerance.” Proceedings of the National Academy of Sciences of the United States of America 105, no. 41 (October 14, 2008): 15819–24. https://doi.org/10.1073/pnas.0807606105.

Han, Yu Mi, Roberto Romero, Jung-Sun Kim, Adi L. Tarca, Sun Kwon Kim, Sorin Draghici, Juan Pedro Kusanovic, et al. “Region-Specific Gene Expression Profiling: Novel Evidence for Biological Heterogeneity of the Human Amnion.” Biology of Reproduction 79, no. 5 (November 2008): 954–61. https://doi.org/10.1095/biolreprod.108.069260.

Tarca, Adi Laurentiu, Sorin Draghici, and Roberto Romero. “Developing Classifiers for the Detection of Cancer Using Multi-Analytes.” Methods in Molecular Biology (Clifton, N.J.) 520 (2009): 259–72. https://doi.org/10.1007/978-1-60327-811-9_19.

Montenegro, D., R. Romero, S. S. Kim, A. L. Tarca, S. Draghici, J. P. Kusanovic, J. S. Kim, et al. “Expression Patterns of MicroRNAs in the Chorioamniotic Membranes: A Role for MicroRNAs in Human Pregnancy and Parturition.” The Journal of Pathology 217, no. 1 (January 2009): 113–21. https://doi.org/10.1002/path.2463.

Tarca, Adi Laurentiu, Sorin Draghici, Purvesh Khatri, Sonia S. Hassan, Pooja Mittal, Jung-Sun Kim, Chong Jai Kim, Juan Pedro Kusanovic, and Roberto Romero. “A Novel Signaling Pathway Impact Analysis.” Bioinformatics (Oxford, England) 25, no. 1 (January 1, 2009): 75–82. https://doi.org/10.1093/bioinformatics/btn577.

Separovic, D., J. Bielawski, J. S. Pierce, S. Merchant, A. L. Tarca, B. Ogretmen, and M. Korbelik. “Increased Tumour Dihydroceramide Production after Photofrin-PDT Alone and Improved Tumour Response after the Combination with the Ceramide Analogue LCL29. Evidence from Mouse Squamous Cell Carcinomas.” British Journal of Cancer 100, no. 4 (February 24, 2009): 626–32. https://doi.org/10.1038/sj.bjc.6604896.

Kim, Mi Jeong, Roberto Romero, Chong Jai Kim, Adi L. Tarca, Sovantha Chhauy, Christopher LaJeunesse, Deug-Chan Lee, et al. “Villitis of Unknown Etiology Is Associated with a Distinct Pattern of Chemokine Up-Regulation in the Feto-Maternal and Placental Compartments: Implications for Conjoint Maternal Allograft Rejection and Maternal Anti- Fetal Graft-versus-Host Disease.” Journal of Immunology (Baltimore, Md. : 1950) 182, no. 6 (March 15, 2009): 3919–27. https://doi.org/10.4049/jimmunol.0803834.

Patel, Bhaumik B., Yingjie Yu, Jianhua Du, Arun K. Rishi, Fazlul H. Sarkar, Adi L. Tarca, Anil Wali, and Adhip P. N. Majumdar. “Schlafen 3, a Novel Gene, Regulates Colonic Mucosal Growth during Aging.” American Journal of Physiology. Gastrointestinal and Liver Physiology 296, no. 4 (April 2009): G955-962. https://doi.org/10.1152/ajpgi.90726.2008.

Than, Nandor Gabor, Roberto Romero, Morris Goodman, Amy Weckle, Jun Xing, Zhong Dong, Yi Xu, et al. “A Primate Subfamily of Galectins Expressed at the Maternal-Fetal Interface That Promote Immune Cell Death.” Proceedings of the National Academy of Sciences of the United States of America 106, no. 24 (June 16, 2009): 9731–36. https://doi.org/10.1073/pnas.0903568106.

Yang, Zeng-Quan, Gang Liu, Aliccia Bollig-Fischer, Ramsi Haddad, Adi L. Tarca, and Stephen P. Ethier. “Methylation-Associated Silencing of SFRP1 with an 8p11-12 Amplification Inhibits Canonical and Non-Canonical WNT Pathways in Breast Cancers.” International Journal of Cancer 125, no. 7 (October 1, 2009): 1613–21. https://doi.org/10.1002/ijc.24518.

Than, Nandor Gabor, Roberto Romero, Adi L. Tarca, Sorin Draghici, Offer Erez, Tinnakorn Chaiworapongsa, Yeon Mee Kim, Sun Kwon Kim, Edi Vaisbuch, and Gerard Tromp. “Mitochondrial Manganese Superoxide Dismutase MRNA Expression in Human Chorioamniotic Membranes and Its Association with Labor, Inflammation, and Infection.” The Journal of Maternal-Fetal & Neonatal Medicine : The Official Journal of the European Association of Perinatal Medicine, the Federation of Asia and Oceania Perinatal Societies, the International Society of Perinatal Obstetricians 22, no. 11 (November 2009): 1000–1013. https://doi.org/10.3109/14767050903019676.

Mittal, Pooja, Roberto Romero, Shali Mazaki-Tovi, Gerard Tromp, Adi L. Tarca, Yeon Mee Kim, Tinnakorn Chaiworapongsa, et al. “Fetal Membranes as an Interface between Inflammation and Metabolism: Increased Aquaporin 9 Expression in the Presence of Spontaneous Labor at Term and Chorioamnionitis.” The Journal of Maternal-Fetal & Neonatal Medicine : The Official Journal of the European Association of Perinatal Medicine, the Federation of Asia and Oceania Perinatal Societies, the International Society of Perinatal Obstetricians 22, no. 12 (December 2009): 1167–75. https://doi.org/10.3109/14767050903019692.

Hassan, Sonia S., Roberto Romero, Adi L. Tarca, Chia-Ling Nhan-Chang, Edi Vaisbuch, Offer Erez, Pooja Mittal, et al. “The Transcriptome of Cervical Ripening in Human Pregnancy before the Onset of Labor at Term: Identification of Novel Molecular Functions Involved in This Process.” The Journal of Maternal-Fetal & Neonatal Medicine : The Official Journal of the European Association of Perinatal Medicine, the Federation of Asia and Oceania Perinatal Societies, the International Society of Perinatal Obstetricians 22, no. 12 (December 2009): 1183–93. https://doi.org/10.3109/14767050903353216.

Erez, Offer, Roberto Romero, Adi L. Tarca, Tinnakorn Chaiworapongsa, Yeon Mee Kim, Nandor Gabor Than, Edi Vaisbuch, Sorin Draghici, and Gerard Tromp. “Differential Expression Pattern of Genes Encoding for Anti-Microbial Peptides in the Fetal Membranes of Patients with Spontaneous Preterm Labor and Intact Membranes and Those with Preterm Prelabor Rupture of the Membranes.” The Journal of Maternal-Fetal & Neonatal Medicine : The Official Journal of the European Association of Perinatal Medicine, the Federation of Asia and Oceania Perinatal Societies, the International Society of Perinatal Obstetricians 22, no. 12 (December 2009): 1103–15. https://doi.org/10.3109/14767050902994796.

Chaiworapongsa, Tinnakorn, Roberto Romero, Adi Tarca, Juan Pedro Kusanovic, Pooja Mittal, Sun Kwon Kim, Francesca Gotsch, et al. “A Subset of Patients Destined to Develop Spontaneous Preterm Labor Has an Abnormal Angiogenic/Anti-Angiogenic Profile in Maternal Plasma: Evidence in Support of Pathophysiologic Heterogeneity of Preterm Labor Derived from a Longitudinal Study.” The Journal of Maternal-Fetal & Neonatal Medicine : The Official Journal of the European Association of Perinatal Medicine, the Federation of Asia and Oceania Perinatal Societies, the International Society of Perinatal Obstetricians 22, no. 12 (December 2009): 1122–39. https://doi.org/10.3109/14767050902994838.

Kato, Ikuko, Kawsar Z. Badsha, Susan Land, Jordan M. Nechvatal, Larry H. Matherly, Adi L. Tarca, Adhip P. Majumdar, Marc D. Basson, and Jeffrey L. Ram. “DNA/RNA Markers for Colorectal Cancer Risk in Preserved Stool Specimens: A Pilot Study.” Tumori 95, no. 6 (December 2009): 753–61. https://doi.org/10.1177/030089160909500619.

Hassan, Sonia S., Roberto Romero, Beth Pineles, Adi L. Tarca, Daniel Montenegro, Offer Erez, Pooja Mittal, et al. “MicroRNA Expression Profiling of the Human Uterine Cervix after Term Labor and Delivery.” American Journal of Obstetrics and Gynecology 202, no. 1 (January 2010): 80.e1-8. https://doi.org/10.1016/j.ajog.2009.08.016.

Madsen-Bouterse, Sally A., Roberto Romero, Adi L. Tarca, Juan Pedro Kusanovic, Jimmy Espinoza, Chong Jai Kim, Jung-Sun Kim, Samuel S. Edwin, Ricardo Gomez, and Sorin Draghici. “The Transcriptome of the Fetal Inflammatory Response Syndrome.” American Journal of Reproductive Immunology (New York, N.Y. : 1989) 63, no. 1 (January 2010): 73–92. https://doi.org/10.1111/j.1600-0897.2009.00791.x.

Separovic, Duska, Ameeta Kelekar, Arun K. Nayak, Adi L. Tarca, Kentaro Hanada, Jason S. Pierce, and Jacek Bielawski. “Increased Ceramide Accumulation Correlates with Downregulation of the Autophagy Protein ATG-7 in MCF-7 Cells Sensitized to Photodamage.” Archives of Biochemistry and Biophysics 494, no. 1 (February 1, 2010): 101–5. https://doi.org/10.1016/j.abb.2009.11.023.

Nhan-Chang, Chia-Ling, Roberto Romero, Adi L. Tarca, Pooja Mittal, Juan Pedro Kusanovic, Offer Erez, Shali Mazaki-Tovi, et al. “Characterization of the Transcriptome of Chorioamniotic Membranes at the Site of Rupture in Spontaneous Labor at Term.” American Journal of Obstetrics and Gynecology 202, no. 5 (May 2010): 462.e1-41. https://doi.org/10.1016/j.ajog.2010.02.045.

Chaiworapongsa, Tinnakorn, Roberto Romero, Adi L. Tarca, Juan Pedro Kusanovic, Francesca Gotsch, Pooja Mittal, Sun Kwon Kim, et al. “A Decrease in Maternal Plasma Concentrations of SVEGFR-2 Precedes the Clinical Diagnosis of Preeclampsia.” American Journal of Obstetrics and Gynecology 202, no. 6 (June 2010): 550.e1-10. https://doi.org/10.1016/j.ajog.2010.04.002.

Lee, Deug-Chan, Roberto Romero, Chong Jai Kim, Tinnakorn Chaiworapongsa, Adi L. Tarca, JoonHo Lee, Yeon-Lim Suh, et al. “Surfactant Protein-A as an Anti-Inflammatory Component in the Amnion: Implications for Human Pregnancy.” Journal of Immunology (Baltimore, Md. : 1950) 184, no. 11 (June 1, 2010): 6479–91. https://doi.org/10.4049/jimmunol.0903867.

Wang, Ying, Arun K. Rishi, Vineshkumar T. Puliyappadamba, Sunita Sharma, Huanjie Yang, Adi Tarca, Q. Ping Dou, et al. “Targeted Proteasome Inhibition by Velcade Induces Apoptosis in Human Mesothelioma and Breast Cancer Cell Lines.” Cancer Chemotherapy and Pharmacology 66, no. 3 (August 2010): 455–66. https://doi.org/10.1007/s00280-009-1181-8.

Chaiworapongsa, Tinnakorn, Juan Pedro Kusanovic, Zeynep Alpay Savasan, Shali Mazaki-Tovi, Sun Kwon Kim, Edi Vaisbuch, Adi L. Tarca, et al. “Fetal Death: A Condition with a Dissociation in the Concentrations of Soluble Vascular Endothelial Growth Factor Receptor-2 between the Maternal and Fetal Compartments.” The Journal of Maternal-Fetal & Neonatal Medicine : The Official Journal of the European Association of Perinatal Medicine, the Federation of Asia and Oceania Perinatal Societies, the International Society of Perinatal Obstetricians 23, no. 9 (September 2010): 960–72. https://doi.org/10.3109/14767050903410664.